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May 24, 2012

Hispanos and Sephardic ancestry

Filed under: Anthroplogy,Hispanos,History — Razib Khan @ 11:06 am

A correspondent emailed me to tell me that Linda Chavez, whose father was a New Mexican Hispano, was found to have Sephardic Jewish ancestry in Henry Louise Gates Jr’s Finding your Roots series. This brings me to point to a recent paper, The impact of Converso Jews on the genomes of modern Latin Americans:

Modern day Latin America resulted from the encounter of Europeans with the indigenous peoples of the Americas in 1492, followed by waves of migration from Europe and Africa. As a result, the genomic structure of present day Latin Americans was determined both by the genetic structure of the founding populations and the numbers of migrants from these different populations. Here, we analyzed DNA collected from two well-established communities in Colorado (33 unrelated individuals) and Ecuador (20 unrelated individuals) with a measurable prevalence of the BRCA1 c.185delAG and the GHR c.E180 mutations, respectively, using Affymetrix Genome-wide Human SNP 6.0 arrays to identify their ancestry. These mutations are thought to have been brought to these communities by Sephardic Jewish progenitors. Principal component analysis and clustering methods were employed to determine the genome-wide patterns of continental ancestry within both populations using single nucleotide polymorphisms, complemented by determination of ...

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