Category Archives: 1000 Genomes

This is an important preprint, Legacy Data Confounds Genomics Studies: Recent reports have identified differences in the mutational spectra across human populations. While some of these reports have been replicated in other cohorts, most have been reported only in the 1000 Genomes Project (1kGP) data. While investigating an intriguing putative population stratification within the Japanese […]

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I don’t have time for this, but I’m sure some readers do. 1000 Genomes has put a tutorial up. Breakdown: 1. Description of the 1000 Genomes Data, Gabor Marth pdf|pptx 2. How to access the Data, Paul Flicek pdf|pptx 3. Lessons in variant calling and genotyping, Hyun Min Kang pdf|pptx 4. Structural Variants, Ryan Mills pdf|pptx 5. Imputation in […]

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I don’t have time for this, but I’m sure some readers do. 1000 Genomes has put a tutorial up. Breakdown: 1. Description of the 1000 Genomes Data, Gabor Marth pdf|pptx 2. How to access the Data, Paul Flicek pdf|pptx 3. Lessons in variant calling and genotyping, Hyun Min Kang pdf|pptx 4. Structural Variants, Ryan Mills pdf|pptx 5. Imputation in […]

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Looks like there have been some changes to the populations in the 1000 Genomes: At least we’ll be able to answer questions about the origin of the Sinhalese soon enough. I’m a little bummed that the Indian populations in Maharashtra …

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The Pith: You are expected to have 30 new mutations which differentiate you from your parents. But, there is wiggle room around this number, and you may have more or less. This number may vary across siblings, and explain differences across siblings. …

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I was semi-offline for much of last week, so I only randomly heard from someone about the “Science paper” on which Molly Przeworski is an author. Finally having a chance to read it front to back it seems rather a complement to other papers…

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Tishkoff et al.
Reading Peter Bellwood’s First Farmers: The Origins of Agricultural Societies, I’m struck by how much of a difference five years has made. When Bellwood was writing the ‘orthodoxy’ of the nature of the expansion of farming into Europe leaned toward cultural diffusion. Today the paradigm is in flux, as a new generation of […]

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7/7
Razib Khan