Category Archives: Genetics

The paper Papua New Guinean Genomes Reveal the Complex Settlement of North Sahul came out a few months ago. It’s fine. But one thing jumped out at me: All estimated […]

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Genetic continuity of Indo-Iranian speakers since the Iron Age in southern Central Asia: To model Tajiks, all 2-ways admixture models were excluded and we obtained one 3-ways admixture model (p-value = 0.49) implying around 17% ancestry from XiongNu, almost 75% ancestry from Turkmenistan_IA, and around 8% ancestry from a South Asian individual (Indian_GreatAndaman_100BP) representing a … Continue reading South Asian ancestry in Tajikistan

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Since people ask me this I have to post this now and then. We have genetic data. So in short order 1) Kashmiris are like other people in the Northwest of India. They are not enriched in steppe ancestry, at least compared to many Punjabis or Brahmins from the Gangetic plain 2) There is no […]

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High-profile autism genetics project paused amid backlash: But soon after the study’s high-profile launch on 24 August, autistic people and some ASD researchers expressed concern that it had gone ahead […]

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A new paper digs into OAS1, A prenylated dsRNA sensor protects against severe COVID-19: Inherited genetic factors can influence the severity of COVID-19, but the molecular explanation underpinning a genetic […]

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The traditional model, which I’ve alluded to before on this weblog before, is that Japan is a synthesis of Jomon and Yayoi, with the latter dominant, and bringing rice-agriculture to […]

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The paper is not out, but since the data has been uploaded they posted the abstract for the world to see, Project: PRJEB44430: Horse domestication fundamentally transformed long-range mobility and warfare. However, modern domesticates do not descend from the earliest domestic horse lineage associated with archaeological evidence of bridling, milking and corralling at Botai, Central […]

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Over on Twitter the eminent population geneticist Molly Przeworski has an important and lauded thread up: The thread has been widely re-tweeted and quote-tweeted by biologists. This prompted a response […]

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I ran a Clubhouse last night on Nepalese genetics. I said something to the effect that most Nepalese Brahmins have Tibetan admixture. A Nepalese Brahmin came up on stage to tell me this was inaccurate, and that they did not intermarry with native people. To give the benefit of the doubt I went back and […]

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Both conservatives and liberals are ignoring the realities of biology

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Looking at the Y chromosomes in the Indian subcontinent, it seems that haplogroups C (found in lots of Patels) and F are the only ones with “eastern” affinity that deeply rooted in the subcontinent. Thoughts? H is found in a lot of Adivasi, but seems more related to West Eurasian populations. This is on my …

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In the annoying dick-swinging competition that are the comments-board, someone asserted Pakistanis have a lot of steppe even on the maternal side. Really?   We have Sintashta mtDNA and the discordance was shocking to me. But there are some groups in Pakistan with detectable Sintashta mtDNA. These samples from Hazara, Kho, Pashtun, Kashmiri,and Kalash. They …

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Region I1 I2*/I2a I2b R1a R1b G J2 J*/J1 E1b1b T Q N Russia 5 10.5 0 46 6 1 3 0 2.5 1.5 1.5 23 Lithuania 6 6 1 […]

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This is not the most important paper, but it is a contribution: Complete mitogenomes document substantial genetic contribution from the Eurasian Steppe into northern Pakistani Indo-Iranian speakers. Abstract: To elucidate whether Bronze Age population dispersals from the Eurasian Steppe to South Asia contributed to the gene pool of Indo-Iranian-speaking groups, we analyzed 19,568 mitochondrial DNA …

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I am hosting a Clubhouse room this Friday, 9 PM CDT (8:30 AM in India on Saturday). The topic will be the genetics of India, and I’ll be talking about my two posts on Substack: – The Stark Truth About Aryans – The Stark Truth About Humans It’s basically going to be an interactive discussion. …

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This is a common question/assertion in the comments pretty much every other week: why couldn’t the documented incursions of nomadic people in the first millennium A.D. be responsible for the steppe ancestry? There is actually a good explanation in The formation of human populations in South and Central Asia, so I’ll quote it: By the …

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My Substack piece is up, Stark Truth About Aryans: a story of India. I’m pretty proud of this, as it wasn’t a single-sitting blog post, but something I worked over several times. Since it’s for paid subscribers I’ll post the first few paragraphs below, with an infographic that I think illustrates a lot of what’s …

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Over at my other weblog I put up a post, Indian Ancestry In Southeast Asia Is Older Than Statistical Genetic Tests Suggest. If you look at two populations in Southeast Asia and find one has Indian ancestry you often can’t find the admixture older than 1000 A.D. (in peninsular Malaysia there is more recent intermarriage …

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Since this question always comes up at some point, I decided to do a rough back-of-the-envelope calculation of the % steppe across the Indian subcontinent. The way I did it was by taking Pakistan, Bangladesh, and India, and estimating the average percentage from the caste breakdowns (e.g., UP is 20% “upper caste” and 20% “Dalit” …

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Razib Khan