{"id":18712,"date":"2010-07-19T14:20:12","date_gmt":"2010-07-19T22:20:12","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=4971"},"modified":"2010-07-19T14:20:12","modified_gmt":"2010-07-19T22:20:12","slug":"genome-wide-association-for-newbies","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2010\/07\/19\/genome-wide-association-for-newbies\/","title":{"rendered":"Genome-wide association for newbies"},"content":{"rendered":"<p>It looks like <a href=\"http:\/\/www.genomesunzipped.org\/\">Genomes Unzipped<\/a> has their own <a href=\"http:\/\/en.wikipedia.org\/wiki\/How_to_Read_a_Book\">Mortimer Adler<\/a>, with an excellent posting, <a href=\"http:\/\/www.genomesunzipped.org\/2010\/07\/how-to-read-a-genome-wide-association-study.php\">How to read a genome-wide association study<\/a>. For those outside the biz I suspect that #4, replication, is going to be the easiest. In the early 2000s a biologist who&#8217;d been in the business for a while cautioned about reading too much into early association results which were sexy, as the same had occurred when <a href=\"http:\/\/www.gnxp.com\/blog\/2006\/07\/linkage-versus-association-mini-primer.php\">linkage studies<\/a> were all the vogue, but replication was not to be. Goes to show that <b>history of science can be useful on a very pragmatic level.<\/b> It can give you a sense of perspective on the evanescent impact of some techniques over the long run.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>It looks like Genomes Unzipped has their own Mortimer Adler, with an excellent posting, How to read a genome-wide association study. For those outside the biz I suspect that #4, replication, is going to be the easiest. In the early 2000s a biologist who&#8217;d been in the business for a while cautioned about reading too [&#8230;]<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[472,82,473],"tags":[],"class_list":["post-18712","post","type-post","status-publish","format-standard","hentry","category-genome-wide-association","category-genomics","category-gwas"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/18712","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=18712"}],"version-history":[{"count":2,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/18712\/revisions"}],"predecessor-version":[{"id":18870,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/18712\/revisions\/18870"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=18712"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=18712"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=18712"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}