{"id":36552,"date":"2011-01-17T09:22:49","date_gmt":"2011-01-17T17:22:49","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=9184"},"modified":"2011-01-21T12:54:57","modified_gmt":"2011-01-21T20:54:57","slug":"introducing-the-harappa-ancestry-project","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/01\/17\/introducing-the-harappa-ancestry-project\/","title":{"rendered":"Introducing the Harappa Ancestry Project"},"content":{"rendered":"<p>A few weeks ago I hinted at a South Asian equivalent to <a href=\"http:\/\/dodecad.blogspot.com\/\">Dodecad<\/a> &amp; <a href=\"http:\/\/bga101.blogspot.com\/\">Eurogenes BGA<\/a>. It is now public and in the data collection phase. You can read the whole thing here:<\/p>\n<p><a href=\"http:\/\/www.zackvision.com\/weblog\/2011\/01\/harappa-ancestry-project\/\">http:\/\/www.zackvision.com\/weblog\/2011\/01\/harappa-ancestry-project<\/a><\/p>\n<p>This is the feed:<\/p>\n<p><a href=\"http:\/\/www.zackvision.com\/weblog\/category\/harappa\/feed\/\">http:\/\/www.zackvision.com\/feed\/<\/a><\/p>\n<p>If your ancestry is from these nations:<\/p>\n<p>Afghanistan<br \/>\nBangladesh<br \/>\nBhutan<br \/>\nBurma<br \/>\nIndia<br \/>\nIran<br \/>\nMaldives<br \/>\nNepal<br \/>\nPakistan<br \/>\nSri Lanka<br \/>\nTibet<\/p>\n<p>Read on! If not, &#8220;for entertainment purposes only&#8221;&#8230;.<\/p>\n<p>\nI have been griping in public and in private about the &#8220;reference&#8221; populations used for South Asian genomics for years. Because of the Permit Raj the HGDP had to use Pakistani populations. Additionally, because of the HGDP&#8217;s mandate to focus on smaller groups which might harbor genetic uniqueness you have some very obscure tribes, but only one sample set from an Indo-Aryan speaking population. And even there, it was a minority, not the Punjabi speaking majority of Pakistan.<\/p>\n<p>Some of this has changed in recent years. Papers such as <a href=\"http:\/\/www.nature.com\/nature\/journal\/v461\/n7263\/abs\/nature08365.html\">Reconstructing Indian History<\/a> and <a href=\"http:\/\/genomebiology.com\/2010\/11\/11\/R113\/abstract\">Genetic diversity in India and the inference of Eurasian population expansion<\/a> have added more populations to the mix. The current phase of the HapMap has <a href=\"http:\/\/ccr.coriell.org\/sections\/collections\/nhgri\/IndSamples.aspx?PgId=435&amp;did=HAPMAP19\">Gujaratis from Houston<\/a>. But there is always a problem when you take a small population set to be representative of a broader group. There are ~1.3 &#8230;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A few weeks ago I hinted at a South Asian equivalent to Dodecad &amp; Eurogenes BGA. It is now public and in the data collection phase. You can read the whole thing here:<br \/>\nhttp:\/\/www.zackvision.com\/weblog\/2011\/01\/harappa-ancestry-project<br \/>\nThis is the fee&#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,82,998],"tags":[],"class_list":["post-36552","post","type-post","status-publish","format-standard","hentry","category-genetics","category-genomics","category-harappa-ancestry-project"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/36552","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=36552"}],"version-history":[{"count":5,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/36552\/revisions"}],"predecessor-version":[{"id":36693,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/36552\/revisions\/36693"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=36552"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=36552"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=36552"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}