{"id":37572,"date":"2011-02-11T11:12:03","date_gmt":"2011-02-11T19:12:03","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=9871"},"modified":"2011-02-11T11:12:03","modified_gmt":"2011-02-11T19:12:03","slug":"%e2%80%9cinadvertent%e2%80%9d-incest-detection","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/02\/11\/%e2%80%9cinadvertent%e2%80%9d-incest-detection\/","title":{"rendered":"\u201cInadvertent\u201d incest detection?"},"content":{"rendered":"<p><a href=\"http:\/\/accidentalblogger.typepad.com\/\">Ruchira<\/a> and <a href=\"http:\/\/www.futurepundit.com\/archives\/007894.html\">Randall Parker<\/a> point me to a new story about routine genomics screens <a href=\"http:\/\/www.chron.com\/disp\/story.mpl\/metropolitan\/7422653.html\">detecting first degree incest<\/a>:<\/p>\n<blockquote>\n<p>Beaudet wrote in the letter that &#8220;clinicians uncovering a likely incestuous relationship may be legally required to report it to child protection services and, potentially, law enforcement officials&#8221; since the pregnancy might have occurred &#8220;in the setting of sexual abuse.&#8221;<\/p>\n<p>The letter was prompted by a Baylor laboratory&#8217;s discoveries that developmental disorders in a number of pediatric patients were caused by incestuous relations not previously disclosed to doctors.<\/p>\n<p>The testing is done to find the disorder&#8217;s genetic basis, typically involving mutations, deletions or duplications. <b>But large blocks of identical DNA are evidence the child&#8217;s parentage involved first-degree relatives.<\/b><\/p>\n<\/blockquote>\n<p>If you&#8217;re curious if you are the product of incest, <a href=\"http:\/\/www.math.mun.ca\/~dapike\/FF23utils\/roh.php\">David Pike&#8217;s runs of homozygosity (ROH) detector<\/a> (Mozilla only) might be useful if you have a genotype file. Sometimes I wonder if mass technology is going to come to fruition far earlier than it takes to write up editorials and publish them.<\/p>\n<p>Of course even people who are not the product of first-degree incest can have very long ROH. Look at <a href=\"http:\/\/www.zackvision.com\/weblog\/2011\/01\/inbreeding\/\">Zack<\/a> (though is in part a legacy of the consanguineous marriage practices common &#8230;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ruchira and Randall Parker point me to a new story about routine genomics screens detecting first degree incest:<br \/>\nBeaudet wrote in the letter that &#8220;clinicians uncovering a likely incestuous relationship may be legally required to report it to chil&#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,82,592],"tags":[],"class_list":["post-37572","post","type-post","status-publish","format-standard","hentry","category-genetics","category-genomics","category-incest"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/37572","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=37572"}],"version-history":[{"count":0,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/37572\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=37572"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=37572"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=37572"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}