{"id":37600,"date":"2011-02-12T03:09:12","date_gmt":"2011-02-12T11:09:12","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=9879"},"modified":"2011-02-23T10:33:39","modified_gmt":"2011-02-23T18:33:39","slug":"a-problem-of-aggregation-of-information","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/02\/12\/a-problem-of-aggregation-of-information\/","title":{"rendered":"A problem of aggregation of information"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2011\/02\/HGDPme-1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-9880\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2011\/02\/HGDPme-1.png\" alt=\"\" width=\"350\" height=\"174\" \/><\/a>In a post below <a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2011\/02\/d-i-y-pca\/\">I regenerated the HGDP PCA plot<\/a> you&#8217;ve probably seen around,\u00a0except that I added my parents (and a few HapMap populations) into the plot. The PCA below was basically a visualization of the two largest <em>independent dimensions<\/em> of genetic variance in the data set. It wasn&#8217;t to scale, as the vertical African vs. non-African dimension is somewhat greater than the horizontal west vs. east dimension in magnitude. But, I argued that the positioning of my parents was deceptive as to their heritage. In the <a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2011\/02\/d-i-y-pca\/#comment-57660\">comments<\/a> John Emerson offers a hypothesis to salvage the possibility that the PCA is telling us something informative about my parents&#8217; relationship to the Uyghurs:<\/p>\n<blockquote>\n<p>Was there ever an endogenous Mughal group in South Asia? If both your parents distantly came from that group, even though assimilated to the local populations for a few generations, the Uighur connection would be unremarkable.<\/p>\n<\/blockquote>\n<p>Combing the plot I generated with the historical information this is an eminently plausible model. But we need to consider what the PCA is showing us. The position of my parents&#8217; is a reflection of their <strong>average<\/strong> genetic variance in relation to two &#8230;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a post below I regenerated the HGDP PCA plot you&#8217;ve probably seen around,\u00a0except that I added my parents (and a few HapMap populations) into the plot. The PCA below was basically a visualization of the two largest independent dimensions of ge&#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,4,82,360],"tags":[],"class_list":["post-37600","post","type-post","status-publish","format-standard","hentry","category-culture","category-genetics","category-genomics","category-personal-genomics"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/37600","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=37600"}],"version-history":[{"count":10,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/37600\/revisions"}],"predecessor-version":[{"id":38003,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/37600\/revisions\/38003"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=37600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=37600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=37600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}