{"id":38705,"date":"2011-03-15T23:50:31","date_gmt":"2011-03-16T07:50:31","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=10356"},"modified":"2011-03-15T23:50:31","modified_gmt":"2011-03-16T07:50:31","slug":"population-structure-within-africa","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/03\/15\/population-structure-within-africa\/","title":{"rendered":"Population structure within Africa"},"content":{"rendered":"<p>John Hawks, <a href=\"http:\/\/johnhawks.net\/weblog\/reviews\/genomics\/modern\/henn-southern-africa-origins-2011.html\">reviews<\/a> Henn et al., and notes:<\/p>\n<blockquote>\n<p>By the time we find &#8220;modern&#8221; humans in West Asia, the African population had long since diversified into regional populations. This is not news; the mtDNA evidence has suggested for several years that southern Africa and the remainder of sub-Saharan Africa were already regionally differentiated before 120,000 years ago. There have also been hints of this diversification from whole-genome evidence (including the supplement of the Neandertal genome paper last year). Here we have a clear indication that the regionality extends to every African hunter-gatherer population.<\/p>\n<\/blockquote>\n<p>For more than a generation we&#8217;ve stated the conventional wisdom that Africa has more genetic diversity than the rest of the world. And yet far too often we&#8217;ve left it at that. With the bigger data set of Henn et al. you can get a sense that there&#8217;s a fair amount of structured variation <em>within<\/em> Africa which is very interesting. It is not one amorphous undifferentiated Dark Continent. Sarah Tishkoff&#8217;s <a href=\"http:\/\/www.sciencemag.org\/content\/324\/5930\/1035.abstract\">recent work<\/a> has been very informative in this domain, but I&#8217;m looking for what we might find out of whole genome sequencing in particular.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>John Hawks, reviews Henn et al., and notes:<br \/>\nBy the time we find &#8220;modern&#8221; humans in West Asia, the African population had long since diversified into regional populations. This is not news; the mtDNA evidence has suggested for several years &#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,82],"tags":[],"class_list":["post-38705","post","type-post","status-publish","format-standard","hentry","category-genetics","category-genomics"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/38705","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=38705"}],"version-history":[{"count":5,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/38705\/revisions"}],"predecessor-version":[{"id":38975,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/38705\/revisions\/38975"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=38705"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=38705"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=38705"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}