{"id":41125,"date":"2011-05-31T02:20:37","date_gmt":"2011-05-31T10:20:37","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=12089"},"modified":"2011-05-31T02:20:37","modified_gmt":"2011-05-31T10:20:37","slug":"the-mess-that-is-mouse","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/05\/31\/the-mess-that-is-mouse\/","title":{"rendered":"The mess that is mouse"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2011\/05\/800px-Apodemus_sylvaticus_bosmuis.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-12090 alignright\" title=\"800px-Apodemus_sylvaticus_bosmuis\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2011\/05\/800px-Apodemus_sylvaticus_bosmuis.jpg\" alt=\"\" width=\"105\" height=\"120\" \/><\/a>Recently an evolutionary geneticist told me that his colleagues who worked with mice really didn&#8217;t have their stuff together. Actually, his language was a touch more colorful than that. But the gist of the argument seemed plausible enough to me. I tend to avoid reading papers using the mouse as a model organism in genetics because I recall getting confused by the pedigrees and various strain acronyms and abbreviations (nonstandard acronyms and abbreviations have also been a problem for me whenever I try to read developmental genetics). If I want to look at the genetics of a mammal besides a human being I often like to focus on dogs. The breeds of dogs actually mean something to me. There&#8217;s only so many skinned mouse hides I want to stare at.<\/p>\n<p><a href=\"http:\/\/www.researchblogging.org\"><img decoding=\"async\" style=\"border: 0;\" src=\"http:\/\/www.researchblogging.org\/public\/citation_icons\/rb2_large_gray.png\" alt=\"ResearchBlogging.org\" \/><\/a>With all that said there is a huge scientific complex devoted to the mouse. If the house of mouse is a mess, then someone needs to do cleaning at some point. A new paper in <em>Nature Genetics<\/em> starts the process, using <a href=\"http:\/\/en.wikipedia.org\/wiki\/Single-nucleotide_polymorphism\">SNPs<\/a> and  variable intensity oligonucleotides (VINOs) to assess the relationships between distinct &#8230;<img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/GeneExpressionBlog\/~4\/ZYkX3d8eQ_o\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recently an evolutionary geneticist told me that his colleagues who worked with mice really didn&#8217;t have their stuff together. Actually, his language was a touch more colorful than that. But the gist of the argument seemed plausible enough to me. &#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1401,4,481,1402,1403,1404,1405],"tags":[],"class_list":["post-41125","post","type-post","status-publish","format-standard","hentry","category-fancy-mice","category-genetics","category-human-genetics","category-mice","category-model-organism","category-mouse","category-mouse-genetics"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/41125","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=41125"}],"version-history":[{"count":4,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/41125\/revisions"}],"predecessor-version":[{"id":41127,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/41125\/revisions\/41127"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=41125"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=41125"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=41125"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}