{"id":42160,"date":"2011-06-28T13:52:07","date_gmt":"2011-06-28T21:52:07","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=12574"},"modified":"2011-06-28T13:52:07","modified_gmt":"2011-06-28T21:52:07","slug":"%e2%80%9cwhat-if-you%e2%80%99re-wrong%e2%80%9d-%e2%80%93-haplogroup-j","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/06\/28\/%e2%80%9cwhat-if-you%e2%80%99re-wrong%e2%80%9d-%e2%80%93-haplogroup-j\/","title":{"rendered":"\u201cWhat if you\u2019re wrong\u201d \u2013 haplogroup J"},"content":{"rendered":"

Back when this sort of thing was cutting edge mtDNA haplogroup J<\/a> was a pretty big deal. This was the haplogroup often associated with the demic diffusion of Middle Eastern farmers into Europe. This was the “Jasmine”<\/a> clade in Seven Daughters of Eve<\/a>. A new paper in PLoS ONE<\/em> makes an audacious claim: that J is not a lineage which underwent recent demographic expansion, but rather one which has been subject to a specific set of evolutionary dynamics which have skewed the interpretations due to a false “molecular clock” assumption.<\/strong> By this assumption, I mean that mtDNA, which is passed down in an unbroken chain from mother to daughter, is by and large neutral to forces like natural selection and subject to a constant mutational rate which can serve as a calibration clock to the last common ancestor between two different lineages. Additionally, mtDNA has a high mutational rate, so it accumulates lots of variation to sample, and, it is copious, so easy to extract. What’s not to like?<\/p>\n

First, the paper, Mutation Rate Switch inside Eurasian Mitochondrial Haplogroups: Impact of Selection and Consequences for Dating Settlement in Europe<\/a>:<\/p>\n<\/p>\n

\n

R-lineage mitochondrial DNA represents over 90% of the European …<\/p>\n","protected":false},"excerpt":{"rendered":"

Back when this sort of thing was cutting edge mtDNA haplogroup J was a pretty big deal. This was the haplogroup often associated with the demic diffusion of Middle Eastern farmers into Europe. This was the “Jasmine” clade in Seven Daughters…<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[101,9,4,82,1567,19,206,208,865,895],"tags":[],"class_list":["post-42160","post","type-post","status-publish","format-standard","hentry","category-agriculture","category-anthroplogy","category-genetics","category-genomics","category-haplogroup-j","category-history","category-mtdna","category-natural-selection","category-neolithic","category-paleolithic"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/42160","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=42160"}],"version-history":[{"count":3,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/42160\/revisions"}],"predecessor-version":[{"id":42307,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/42160\/revisions\/42307"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=42160"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=42160"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=42160"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}