{"id":59232,"date":"2011-12-28T23:05:20","date_gmt":"2011-12-29T07:05:20","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=15063"},"modified":"2011-12-28T23:05:20","modified_gmt":"2011-12-29T07:05:20","slug":"basque-genetic-distinctiveness-again","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/12\/28\/basque-genetic-distinctiveness-again\/","title":{"rendered":"Basque genetic distinctiveness (again)"},"content":{"rendered":"<p>With all the talk about <a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2011\/12\/the-basques-are-genetically-distinctive\/\">Basques<\/a> I decided to do my own analysis with <a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2011\/03\/analyzing-ancestry-with-admixture-step-by-step\/\">Admixture<\/a>. <a href=\"http:\/\/dienekes.blogspot.com\/\">Dienekes<\/a> gave me a copy of his IBS file, which has all the 1000 Genomes Spanish samples, including Basques. I merged it with the HGDP sample, which has French Basques (just &#8220;Basques&#8221; in the plots below) and French non-Basques. I pruned most of the populations, but kept the Mozabites, which are a Berber group from Algeria. The number of markers was ~350,000, and I ran it up to K = 8, or 8 component populations. I stopped there because the components were starting to break up in a very choppy manner.<\/p>\n<p>In general I do think that <b>the idea that non-Basque Spaniards have Moorish genetic input seems supported.<\/b> It isn&#8217;t definitive though. And you have to be careful, there are lower parameter values where Sardinians seem to have an affinity with Mozabites to a great extent, even more than Spaniards. But that disappears as you move up the number of K&#8217;s. But who is to say which K is the correct K? The consistent Sub-Saharan African among non-Basque Spaniards (also evident in the Behar et al. data set) component  probably convinces me that there was a Moorish impact, since these are likely to have come with the Islamic conquest, and not Phoenicians.<\/p>\n<p>All the files from the Admixture run (and csv files with tabular results) <a href=\"https:\/\/docs.google.com\/open?id=0B8Tdg8RZEWOOZTI5NWNhZDMtN2FjNy00ZTcyLWI3OGUtZTY4MTlhMmY5ODQ0\">are here<\/a>.<\/p>\n<p><span id=\"more-15063\"><\/span><\/p>\n<div class=\"ngg-galleryoverview\" id=\"ngg-gallery-32-15063\">\n<p>\t<!-- Slideshow link --><\/p>\n<div class=\"slideshowlink\">\n\t\t<a class=\"slideshowlink\" href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2011\/12\/basque\/?show=slide\"><br \/>\n\t\t\t[Show as slideshow]\t\t<\/a>\n\t<\/div>\n<p>\t<!-- Piclense link --><\/p>\n<div class=\"piclenselink\">\n\t\t<a class=\"piclenselink\" href=\"javascript:PicLensLite.start(%7BfeedUrl%3A'http%3A\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/plugins\/nextgen-gallery\/xml\/media-rss.php?gid=32&amp;mode=gallery'%7D);\"><br \/>\n\t\t\t[View with PicLens]\t\t<\/a>\n\t<\/div>\n<p>\t<!-- Thumbnails --><\/p>\n<div id=\"ngg-image-143\" class=\"ngg-gallery-thumbnail-box\"  >\n<div class=\"ngg-gallery-thumbnail\" >\n\t\t\t<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/ibs2.png\" title=\" \" class=\"shutterset_set_32\" ><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" title=\"K = 2\" alt=\"K = 2\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/thumbs\/thumbs_ibs2.png\" width=\"100\" height=\"75\" \/><br \/>\n\t\t\t\t\t\t\t<\/a><br \/>\n            <span>K = 2<\/span>\n\t\t<\/div>\n<\/p><\/div>\n<div id=\"ngg-image-144\" class=\"ngg-gallery-thumbnail-box\"  >\n<div class=\"ngg-gallery-thumbnail\" >\n\t\t\t<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/ibs3.png\" title=\" \" class=\"shutterset_set_32\" ><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" title=\"K = 3\" alt=\"K = 3\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/thumbs\/thumbs_ibs3.png\" width=\"100\" height=\"75\" \/><br \/>\n\t\t\t\t\t\t\t<\/a><br \/>\n            <span>K = 3<\/span>\n\t\t<\/div>\n<\/p><\/div>\n<div id=\"ngg-image-145\" class=\"ngg-gallery-thumbnail-box\"  >\n<div class=\"ngg-gallery-thumbnail\" >\n\t\t\t<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/ibs4.png\" title=\" \" class=\"shutterset_set_32\" ><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" title=\"K = 4\" alt=\"K = 4\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/thumbs\/thumbs_ibs4.png\" width=\"100\" height=\"75\" \/><br \/>\n\t\t\t\t\t\t\t<\/a><br \/>\n            <span>K = 4<\/span>\n\t\t<\/div>\n<\/p><\/div>\n<div id=\"ngg-image-146\" class=\"ngg-gallery-thumbnail-box\"  >\n<div class=\"ngg-gallery-thumbnail\" >\n\t\t\t<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/ibs5.png\" title=\" \" class=\"shutterset_set_32\" ><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" title=\"K = 5\" alt=\"K = 5\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/thumbs\/thumbs_ibs5.png\" width=\"100\" height=\"75\" \/><br \/>\n\t\t\t\t\t\t\t<\/a><br \/>\n            <span>K = 5<\/span>\n\t\t<\/div>\n<\/p><\/div>\n<div id=\"ngg-image-147\" class=\"ngg-gallery-thumbnail-box\"  >\n<div class=\"ngg-gallery-thumbnail\" >\n\t\t\t<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/ibs6.png\" title=\" \" class=\"shutterset_set_32\" ><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" title=\"K = 6\" alt=\"K = 6\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/thumbs\/thumbs_ibs6.png\" width=\"100\" height=\"75\" \/><br \/>\n\t\t\t\t\t\t\t<\/a><br \/>\n            <span>K = 6<\/span>\n\t\t<\/div>\n<\/p><\/div>\n<div id=\"ngg-image-148\" class=\"ngg-gallery-thumbnail-box\"  >\n<div class=\"ngg-gallery-thumbnail\" >\n\t\t\t<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/ibs7.png\" title=\" \" class=\"shutterset_set_32\" ><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" title=\"K = 7\" alt=\"K = 7\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/thumbs\/thumbs_ibs7.png\" width=\"100\" height=\"75\" \/><br \/>\n\t\t\t\t\t\t\t<\/a><br \/>\n            <span>K = 7<\/span>\n\t\t<\/div>\n<\/p><\/div>\n<div id=\"ngg-image-149\" class=\"ngg-gallery-thumbnail-box\"  >\n<div class=\"ngg-gallery-thumbnail\" >\n\t\t\t<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/ibs8.png\" title=\" \" class=\"shutterset_set_32\" ><br \/>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" title=\"K = 8\" alt=\"K = 8\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/wp-content\/blogs.dir\/34\/files\/basque\/thumbs\/thumbs_ibs8.png\" width=\"100\" height=\"75\" \/><br \/>\n\t\t\t\t\t\t\t<\/a><br \/>\n            <span>K = 8<\/span>\n\t\t<\/div>\n<\/p><\/div>\n<p>\t<!-- Pagination --><\/p>\n<div class='ngg-clear'><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>With all the talk about Basques I decided to do my own analysis with Admixture. Dienekes gave me a copy of his IBS file, which has all the 1000 Genomes Spanish samples, including Basques. I merged it with the HGDP sample, which has French Basques (just &#8220;Basques&#8221; in the plots below) and French non-Basques. I [&#8230;]<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[290,1890,360],"tags":[],"class_list":["post-59232","post","type-post","status-publish","format-standard","hentry","category-admixture","category-basques","category-personal-genomics"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/59232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=59232"}],"version-history":[{"count":10,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/59232\/revisions"}],"predecessor-version":[{"id":59570,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/59232\/revisions\/59570"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=59232"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=59232"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=59232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}