{"id":59292,"date":"2011-12-29T10:54:28","date_gmt":"2011-12-29T18:54:28","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=15071"},"modified":"2011-12-29T10:54:28","modified_gmt":"2011-12-29T18:54:28","slug":"noninvasive-tests-for-down-syndrome","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2011\/12\/29\/noninvasive-tests-for-down-syndrome\/","title":{"rendered":"Noninvasive tests for Down Syndrome"},"content":{"rendered":"<p>I&#8217;ve mentioned this before, but I thought I&#8217;d pass on the <a href=\"http:\/\/www.genomeweb.com\/sequencing\/sequenom-publish-validation-study-t13-and-t18-dx-plans-improvements-lower-matern\">latest report on MaterniT21<\/a>, the prenatal noninvasive Down Syndrome test. Currently it has a $235 copay for women with insurance. As of now only a few percent of the ~5 million pregnancies in the USA are subject to amnio or <a href=\"http:\/\/en.wikipedia.org\/wiki\/Chorionic_villus_sampling\">c.v.s.<\/a> This procedure may result in the screened proportion going from ~1 percent to ~50 or more percent (though the firm that is providing this can only process ~100,000 tests per year as of now). I stumbled upon this after doing a follow up on my post, <a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2011\/12\/would-you-have-your-fetus-genetically-tested\/\">Would you have your fetus genetically tested?<\/a> Interestingly the proportions who would get tested doesn&#8217;t differ that much between demographics. <\/p>\n<p>And the outcomes can sometimes surprise. A <a href=\"http:\/\/www.dispatch.com\/content\/stories\/local\/2011\/12\/04\/a-chosen-child.html\">story in the Columbus Dispatch<\/a> relates the story of a couple who kept their daughter, who tested positive for Down Syndrome. <b>They had originally decided that if the tests came back positive the would terminate.<\/b> In contrast, the nurses relate that one strongly anti-abortion couple at the beginning of the process seems to have terminated. Right now 1 in 700 pregnancies result in Down Syndrome. <\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/GeneExpressionBlog\/~4\/9f43gtKrnxM\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>I&#8217;ve mentioned this before, but I thought I&#8217;d pass on the latest report on MaterniT21, the prenatal noninvasive Down Syndrome test. Currently it has a $235 copay for women with insurance. As of now only a few percent of the ~5 million pregnancies in the USA are subject to amnio or c.v.s. This procedure may [&#8230;]<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1185,1929],"tags":[],"class_list":["post-59292","post","type-post","status-publish","format-standard","hentry","category-bioethics","category-down-syndrome"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/59292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=59292"}],"version-history":[{"count":3,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/59292\/revisions"}],"predecessor-version":[{"id":59391,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/59292\/revisions\/59391"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=59292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=59292"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=59292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}