{"id":67558,"date":"2012-04-16T22:25:59","date_gmt":"2012-04-17T06:25:59","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=16336"},"modified":"2012-04-16T22:25:59","modified_gmt":"2012-04-17T06:25:59","slug":"reprising-genes-geography","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2012\/04\/16\/reprising-genes-geography\/","title":{"rendered":"Reprising genes &amp; geography"},"content":{"rendered":"<p><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2861313\/?tool=pubmed\">Comparing Spatial Maps of Human Population-Genetic Variation Using Procrustes Analysis<\/a>:<\/p>\n<blockquote>\n<p>Recent applications of principal components analysis (PCA) and multidimensional scaling (MDS) in human population genetics have found that &#8220;statistical maps&#8221; based on the genotypes in population-genetic samples often resemble geographic maps of the underlying sampling locations. To provide formal tests of these qualitative observations, we describe a Procrustes analysis approach for quantitatively assessing the similarity of population-genetic and geographic maps. We confirm in two scenarios, one using single-nucleotide polymorphism (SNP) data from Europe and one using SNP data worldwide,<b> that a measurably high level of concordance exists between statistical maps of population-genetic variation and geographic maps of sampling locations&#8230;.<\/b>\n<\/p>\n<\/blockquote>\n<p>There is concordance. But look at the figure below. On the left are populations where they were sampled, and the right shows the populations displayed in a manner to reflect genetic distances. <\/p>\n<p>\n<a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/proc.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/proc.jpg\" alt=\"\" title=\"proc\" width=\"606\" height=\"507\" class=\"alignnone size-full wp-image-16337\" \/><\/a><\/p>\n<p>I don&#8217;t want to make too much of this. The HGDP populations tend to be sampled from particularly distinctive groups consciously. But it does look like there is a stronger genetic clustering effect than one can predict from geography alone. That warrants investigation. I will leave the rest for &#8230;<img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/GeneExpressionBlog\/~4\/tAtgeld7wBg\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Comparing Spatial Maps of Human Population-Genetic Variation Using Procrustes Analysis:<br \/>\nRecent applications of principal components analysis (PCA) and multidimensional scaling (MDS) in human population genetics have found that &#8220;statistical maps&amp;#&#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9,2011],"tags":[],"class_list":["post-67558","post","type-post","status-publish","format-standard","hentry","category-anthroplogy","category-genes-and-geography"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/67558","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=67558"}],"version-history":[{"count":6,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/67558\/revisions"}],"predecessor-version":[{"id":68013,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/67558\/revisions\/68013"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=67558"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=67558"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=67558"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}