{"id":68087,"date":"2012-04-24T19:40:15","date_gmt":"2012-04-25T03:40:15","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=16427"},"modified":"2012-04-24T19:40:15","modified_gmt":"2012-04-25T03:40:15","slug":"one-baby-alone-on-a-pca-island","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2012\/04\/24\/one-baby-alone-on-a-pca-island\/","title":{"rendered":"One baby, alone on a PCA island"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/razib23andme.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-16358\" title=\"razib23andme\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/razib23andme.jpg\" alt=\"\" width=\"278\" height=\"408\" \/><\/a><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/daughter23andme.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-16359 alignnone\" title=\"daughter23andme\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/daughter23andme.jpg\" alt=\"\" width=\"276\" height=\"406\" \/><\/a><\/p>\n<p><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/baby1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-16437\" title=\"baby\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/baby1.jpg\" alt=\"\" width=\"185\" height=\"247\" \/><\/a>A week ago I reported that according to 23andMe I&#8217;m 40% Asian, and she is 8% Asian (in the future if I say &#8220;she&#8221; without explanation, you know of whom I speak). Obviously something is off here. The situation resolved itself when I tuned my parameters and increased my sampled populations in <a href=\"http:\/\/esquilax.stanford.edu\/\">Interpretome<\/a>. By now\u00a0I&#8217;ve already done the estimates of recombination on the chromosomes which came together to produce her, and the realized value of 8 percent instead of 20 percent &#8220;Asian&#8221; simply can not be due to a particular set of unlikely crossing over events. From what I can gather <strong>it seems like ancestry painting should be viewed as a <em>qualitative<\/em>\u00a0rather than a <em>quantitative<\/em> assessment.<\/strong> This sounds really strange when you are given percentages, but the results are strange, and obviously wrong too often in terms of the specific values.<\/p>\n<p>Here&#8217;s an admixture plot which shows more realistically informative values:<\/p>\n<\/p>\n<p><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/razibdaughteradmix.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-16428\" title=\"razibdaughteradmix\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/razibdaughteradmix.png\" alt=\"\" width=\"374\" height=\"474\" \/><\/a>I&#8217;ve run several admixture plots already with my daughter, and &#8230;<img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/GeneExpressionBlog\/~4\/HLSqmLi0-DM\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A week ago I reported that according to 23andMe I&#8217;m 40% Asian, and she is 8% Asian (in the future if I say &#8220;she&#8221; without explanation, you know of whom I speak). Obviously something is off here. The situation resolved itself when I tu&#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9,360],"tags":[],"class_list":["post-68087","post","type-post","status-publish","format-standard","hentry","category-anthroplogy","category-personal-genomics"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/68087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=68087"}],"version-history":[{"count":4,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/68087\/revisions"}],"predecessor-version":[{"id":68339,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/68087\/revisions\/68339"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=68087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=68087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=68087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}