{"id":68487,"date":"2012-04-29T13:49:10","date_gmt":"2012-04-29T21:49:10","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=16509"},"modified":"2012-04-29T13:49:10","modified_gmt":"2012-04-29T21:49:10","slug":"her-identity-by-descent-made-flesh","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2012\/04\/29\/her-identity-by-descent-made-flesh\/","title":{"rendered":"Her identity by descent made flesh"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/Rplot051.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-16512\" title=\"Rplot05\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2012\/04\/Rplot051.jpg\" alt=\"\" width=\"368\" height=\"224\" \/><\/a>As I have indicated before, my daughter has a family tree where everyone out to 0.25 coefficient of relatedness has been genotyped by 23andMe. This is convenient in many ways. Before, relatedness was a theory. Now relatedness can be ascertained on the genomic level. Sometimes this can lead to peculiar consequences. &#8220;On paper&#8221; my daughter is 1\/8 Scandinavian. Or 12.5%. But truly the expected value is 13.5%! (weighting by contributions from each maternal grandparent). Still, this remains an expected value. I would need a large sample of Scandinavians from that <a href=\"http:\/\/maps.google.com\/maps?q=Oslo,+Norway&amp;hl=en&amp;sll=37.0625,-95.677068&amp;sspn=32.610437,64.248047&amp;t=h&amp;geocode=FY02kgMd9RCkAA&amp;hnear=Oslo,+Norway&amp;z=10\">locale<\/a> to make a truly precise guess as to the genetic contribution. Similarly, though I come in at about ~15 percent East Asian, my daughter looks to be a bit more East Asian than you&#8217;d expect based on that value (i.e., closer to 8-8.5 percent; I run her genotype more than a dozen times now). This may be a bias in the methodology, or, more likely it is simply the sampling error from my genome (I contributed more East Asian segments in the chromosomes passed down).<\/p>\n<p>In any case, 23andMe has a <a href=\"https:\/\/www.23andme.com\/you\/inheritance\/\">&#8220;family inheritance&#8221;<\/a> feature which is very convenient. &#8230;<img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/GeneExpressionBlog\/~4\/TwhGS9WLwgU\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>As I have indicated before, my daughter has a family tree where everyone out to 0.25 coefficient of relatedness has been genotyped by 23andMe. This is convenient in many ways. Before, relatedness was a theory. Now relatedness can be ascertained on the &#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,82,360],"tags":[],"class_list":["post-68487","post","type-post","status-publish","format-standard","hentry","category-genetics","category-genomics","category-personal-genomics"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/68487","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=68487"}],"version-history":[{"count":7,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/68487\/revisions"}],"predecessor-version":[{"id":68804,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/68487\/revisions\/68804"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=68487"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=68487"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=68487"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}