{"id":73653,"date":"2012-08-29T20:22:27","date_gmt":"2012-08-30T04:22:27","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=18090"},"modified":"2012-08-29T20:22:27","modified_gmt":"2012-08-30T04:22:27","slug":"the-eternal-question-of-calorie-restriction","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2012\/08\/29\/the-eternal-question-of-calorie-restriction\/","title":{"rendered":"The eternal question of calorie restriction"},"content":{"rendered":"<p>There&#8217;s a lot of buzz about a new paper in <em>Nature<\/em> (yes, I know there&#8217;s <em>always<\/em> buzz about some <em>Nature<\/em> paper or other), <a href=\"http:\/\/www.nature.com\/nature\/journal\/vaop\/ncurrent\/full\/nature11432.html\">Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study<\/a>. You&#8217;ve probably heard about calorie restriction before. For me the issue I have with it is that people who are very knowledgeable (i.e., researchers who know a great deal abut human physiology, etc.) have given me contradictory assessments of this strategy of life extension. But it&#8217;s not totally crazy, there are serious scientists at top-tier universities who practice calorie restriction themselves. This isn&#8217;t the final word, but I wouldn&#8217;t be surprised if it is going to take decades for it to resolve itself for humans specifically (because some people will always be, and perhaps rightly, extrapolating from short-lived organisms to humans when it comes to modulations of lifespan in the laboratory). \u00a0<em>The New York Times <\/em><a href=\"http:\/\/www.nytimes.com\/2012\/08\/30\/science\/low-calorie-diet-doesnt-prolong-life-study-of-monkeys-finds.html?hp\">piece had a really strange coda<\/a>:<\/p>\n<blockquote>\n<p>Dr. de Cabo, who says he is overweight, advised people that if they want to try a reduced-calorie diet, they should consult a doctor first. If they can handle such a diet, he said, he believes they would be healthier, &#8230;<img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/GeneExpressionBlog\/~4\/r2l3YMnxjnY\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>There&#8217;s a lot of buzz about a new paper in Nature (yes, I know there&#8217;s always buzz about some Nature paper or other), Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. You&#8217;ve probably heard abo&#8230;<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2118,151,58],"tags":[],"class_list":["post-73653","post","type-post","status-publish","format-standard","hentry","category-calorie-restriction","category-diet","category-health"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/73653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=73653"}],"version-history":[{"count":7,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/73653\/revisions"}],"predecessor-version":[{"id":73773,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/73653\/revisions\/73773"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=73653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=73653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=73653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}