{"id":98596,"date":"2013-10-30T18:48:44","date_gmt":"2013-10-31T02:48:44","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/gnxp\/?p=23125"},"modified":"2013-10-30T18:48:44","modified_gmt":"2013-10-31T02:48:44","slug":"the-human-genetic-casserole-3","status":"publish","type":"post","link":"https:\/\/www.razib.com\/wordpress\/2013\/10\/30\/the-human-genetic-casserole-3\/","title":{"rendered":"The human genetic casserole"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2013\/10\/Hotdish.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-23126\" alt=\"Hotdish\" src=\"http:\/\/blogs.discovermagazine.com\/gnxp\/files\/2013\/10\/Hotdish-300x213.jpg\" width=\"300\" height=\"213\" \/><\/a>I haven&#8217;t said much about <a href=\"http:\/\/www.sciencemag.org\/content\/342\/6157\/409.full\">this article in <i>Science<\/i><\/a>, <a href=\"http:\/\/www.sciencemag.org\/content\/342\/6157\/409.full\">Ancient DNA Links Native Americans With Europe<\/a>, because it would be an understatement to say I&#8217;m digesting it. I would offer up a caution that using <b>terms like &#8220;Europeans&#8221; and &#8220;East Asians&#8221; for populations which flourished ~25,000 years ago might be misleading.<\/b> We are used to thinking of genetic distance in terms of space, but time is also a dimension to consider. Populations even without admixture or gene flow will have drifted in allele frequencies over so many generations.<\/p>\n<p>But I have to admit that it seems more and more likely that <b>most extant modern populations are combinations of lineages which diverged <i>very early<\/i> after the &#8220;Out of Africa&#8221; migration.<\/b> We see this clearly with South Asians, and now Europeans and Native Americans. The Reich lab has also found evidence of admixture in <a href=\"http:\/\/www.cell.com\/AJHG\/abstract\/S0002-9297(11)00395-8\">in Australians<\/a>. The closer we look, the more amalgamation we see between disparate lineages. Using the elements of the present to reconstruct the patterns of the past is going to be a more daunting task than most would have guessed.<\/p>\n<p>The post <a rel=\"nofollow\" href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2013\/10\/human-genetic-casserole\/\">The human genetic casserole<\/a> appeared first on <a rel=\"nofollow\" href=\"http:\/\/blogs.discovermagazine.com\/gnxp\">Gene Expression<\/a>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/GeneExpressionBlog\/~4\/n6CkVTB7txM\" height=\"1\" width=\"1\" alt=\"\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>I haven&rsquo;t said much about this article in Science, Ancient DNA Links Native Americans With Europe, because it would be an understatement to say I&rsquo;m digesting it. I would offer up a caution that using terms like &ldquo;Europeans&rdquo; and &ldquo;East Asians&rdquo; for populations which flourished ~25,000 years ago might be misleading. We are used to [&hellip;]<\/p>\n<p>The post <a rel=\"nofollow\" href=\"http:\/\/blogs.discovermagazine.com\/gnxp\/2013\/10\/human-genetic-casserole\/\">The human genetic casserole<\/a> appeared first on <a rel=\"nofollow\" href=\"http:\/\/blogs.discovermagazine.com\/gnxp\">Gene Expression<\/a>.<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[106,2041],"tags":[],"class_list":["post-98596","post","type-post","status-publish","format-standard","hentry","category-archaeology","category-human-history"],"_links":{"self":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/98596","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/comments?post=98596"}],"version-history":[{"count":3,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/98596\/revisions"}],"predecessor-version":[{"id":103008,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/posts\/98596\/revisions\/103008"}],"wp:attachment":[{"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/media?parent=98596"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/categories?post=98596"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.razib.com\/wordpress\/wp-json\/wp\/v2\/tags?post=98596"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}