Razib Khan’s Content Aggregation Site

Natural Selection in Humans

The full episode is available here: https://www.razibkhan.com/p/10000-years-of-selection-in-western Despite the preprint being out for two years, Akbari et al.’s Ancient DNA reveals pervasive directional selection across West Eurasia publication in Nature this week has resulted in a massive media response. Though Razib has discussed this work before, he thought it would be useful to review it, and put it in…

Today Razib talks to Matthew Schmitz, a journalist who previously served as an editor at the religious journal First Things. He is the cofounder of the online magazine Compact, alongside Edwin Aponte and Sohrab Ahmari. He currently serves as editor of Compact, religion editor of Washington Post Opinions, and co-host of the podcast Against the Grain. Compact His essays on politics and culture have appeared in The New…

The rise of the gerontocracy

On this episode of Unsupervised Learning Razib talks to returning guest Megan McArdle. She is the author of The Up Side of Down: Why Failing Well Is the Key to Success and a Washington Post columnist and op-ed board member. McArdle grew up in New York …

You can find the complete monologue here: https://www.razibkhan.com/p/monologue-race-genetics-history-and This is where you will find all the podcasts from Razib Khan’s Substack and original video content. On this episode, Razib talks about race, and h…

You can find the complete monologue here: https://www.razibkhan.com/p/monlogue-out-of-africa-is-not-dead On this episode Razib talks about where we are when it comes to “Out-of-Africa,” Neanderthal origins and the broader state of understanding the dynamics of Homo evolution.

Adaptation in our time

American Religion in 2026

Today Razib talks to Chris Bradley, a serial entrepreneur and the CEO and Co-Founder of Matter Bio, a company dedicated to preserving genome integrity and addressing the root causes of aging. With a multidisciplinary background spanning neuroscience, cell biology, and computer science, Bradley aims to translate early-stage biotech concepts into practical therapies that can extend human lifespan…

Today Razib talks to Chris Bradley, a serial entrepreneur and the CEO and Co-Founder of Matter Bio, a company dedicated to preserving genome integrity and addressing the root causes of aging. With a multidisciplinary background spanning neuroscience, cell biology, and computer science, Bradley aims to translate early-stage biotech concepts into practical therapies that can extend human lifespan…

Washington Post columnist Megan McArdle revisits Unsupervised Learning

Today, Razib talks to Chris Masterjohn, a nutritional scientist and leading expert in mitochondrial biology who believes hidden energy bottlenecks underlie much of modern disease. After years of work as a professor and researcher, he founded Mitome, the first mitochondrial analysis designed for everyday health, and serves as its Scientific Director. His mission is to make mitochondrial…

How should we think about race from a multi-disciplinary perspective?

Human evolution, the recent and the distant

On this episode of Unsupervised Learning, Razib talks to Mike White, a Genetics professor at the Washington University in St. Louis. White has a position at the School of Medicine in St. Louis, where he leads a research team focused on understanding the biophysical architecture of regulatory DNA. He earned a B.A. in music before pivoting…

A biotech entrepreneur talks about how humans might extend their lives

At the intersection of science and well-being

On this episode of Unsupervised Learning Razib talks to Aaron Renn. Renn is a writer, consultant, and urban analyst known for his work on the challenges facing American cities and religious institutions in the 21st century. He is a contributor to The American Reformer and the author of Life in the Negative World, a book exploring the cultural shifts regarding Christianity in America. Renn…

A geneticist at Washington University-St. Louis talks about the cultural and political winds in academia, and the state of genomics in 2026